Does RA originate in the lungs and other mucosal sites?What does it take to create a long-term remission?

Rheumatology

1.How do we treat RA ?
2. Efficacy- How long does a response last?
3. What does it take to create a long-term remission?
4.Does RA originate in the lungs and other mucosal sites?
5. 3 peer reviewed references less than 5 years old