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The Covid-19 pandemic has accelerated the roll out of advanced therapeutics during crisis approval of vaccines such as Oxford/AstraZeneca and Pfizer/BioNTech or Moderna. Compare and contrast the technologies employed in those vaccines with those employed in gene therapy interventions.
Via specific examples, detail the different approved biologic drug types currently therapeutically available for clinical use and discuss their relative advantages over small molecule therapies for those specific disease indications.
One of your fellow students was ill and missed Lab Units 21-22. They have pictures of all of the models, slides, specimens from lab but they are having a hard time putting the images in context. Write a letter to a fellow lab student explaining the two major plant lineages covered in Units 21-22. Use clear, expressive and appropriate language.
You can refer to your lab manual and lecture textbook, but do not include direct quotes. Write the letter entirely in your own words. See below for specific details about what should be included in each paragraph. The assignment will be turned in electronically via Canvas and automatically checked for plagiarism using Turnitin. The letter should include the following:
Header that includes your name and CWID
Times New Roman 12 point font, double spaced
Use appropriate spelling and grammar
Be clear and straightforward
Letter Details
In vitro, TGF-β is one of the most effective inhibitors of hematopoietic stem cell proliferation. TGF-β has been proposed to be a fundamental regulator of HSC quiescence, sustaining a slow-cycling state of HSCs in vivo, due to their inherently quiescent state. In vitro neutralization of TGF-β was demonstrated to wake up early hematopoietic progenitor cells, confirming this theory. Changes in cytokine receptor expression and up-regulation of cyclin-dependent kinase inhibitors such as p15, p21, and p27 have been hypothesized as molecular pathways for TGF-β mediated growth suppression.
Can anyone figure out some examples about TGF- in hematopoietic disease? and any therapeutic avenues?
You should also include historic information. When was PCR invented?
What types of polio vaccines
were tried and failed before we succeeded?
What are the times, the dates, and the people involved?
What was the world like before?
If your topic is relatively new, or something that is still being developed, you may want to include where
the future is heading.
Gene therapy isn’t commonly used now; why not? What needs to be perfected?
How will that be done?
You should discuss the good and bad side of your topic .
What benefits have we
gained from gene therapy?
What are the downfalls of the smallpox vaccine?
How can DNA profiling be
used in positive and negative ways?
Why did/are some people “all for” this topic?
Why are some
people dead set against it?
Article critique , kindly check attached files below for instructions
After summarizing the article, critique the article by doing the following:
• Discuss the strengths and weaknesses of the article that you noted while critically reading the article.
• State your informed opinions about the clarity, relevancy, and accuracy of the article,
using specific examples from the article to support your statements.
• Show your Assessment of the arguments/evidence/method of research /discussions/conclusions presented within the article.
The Nervous System Part 1
Fill in the blanks with:
axon, cell body, dendrites, glial, nerve, nucleus, quickly, stimuli, transmits
Basic Structure of Neurons:
⦁ Define spinal motor neuron:
⦁ Define Soma:
⦁ Where would one find DNA in a neuron?
⦁ Neurons have the genetic information to undergo mitosis but neurons cannot reproduce themselves. What organelle are they lacking?
⦁ What is the function of dendrites?
⦁ Where is an axon hillock located?
⦁ Define axon:
⦁ Define axon terminal:
⦁ Define synapse:
Enzyme and ATP Questions
1) Find an enzyme that is beneficial to the human race, but is NOT a part of our bodies. Describe it and the reaction it works on. Why is it important to us?
2) Why ATP? ATP is used by all cells, whether they are from a bacteria or a human being, as a way to store and transport energy. Why do you think it is that every cell uses this molecule? Why hasn’t an organism come up with a different method of energy production and storage?
USE THE WEBSITES I INCLUDED IN THE ADDITIONAL MATERIALS.
Buffalo National Scenic River – 50th Anniversary
This year, 2022, marks the 50th Anniversary of the FIRST National Scenic River – the Buffalo River, right here in northwest Arkansas! Let’s have a discussion to celebrate and learn more about this ecological treasure in our own backyard.
How humans affect, or threaten, the area’s ecosystem
Unique wildlife, plants, geology present in the area
To earn full points for this assignment, follow this grading rubric:
Discuss something unique and not already brought up by another student
Give 2-4 sentence introduction of your topic, why you feel it is important
Explain which of the learning objectives you are trying to address, or how it is related to this course’s content.
In 1965, Janet Reimer of Winnepeg gave birth to twin boys named Bruce and Brian . Both infants were normal and healthy, but because they had difculty urinating doctors recommended that they undergo circumcision at six months of age. Although this is a routine operation, the doctors who performed this procedure used an unconventional method that resulted in the destruction of Bruce’s penis. Mr. and Mrs.
Questions
1. Some people have argued that the Johns Hopkins psychologist used this opportunity as an experiment to test his nurture theory of gender identity. What are the expected results of this experiment, assuming that the nurture theory is valid?
2. According to the nurture theory, predict the gender identity Bruce would express if he were not subjected to gender re-assignment surgery and raised as a boy?